Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 4/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.52 |
| ▸ | AGT | P01019 | 1/20 | 0.45 |
| ▸ | NAE1 | Q13564 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873571 | 0.94 | AGTR2 (0.56) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL498030 | 0.89 | AGTR1 (0.64) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL9596667 | 0.88 | AGTR1 (0.41) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL28915096 | 0.88 | AGTR2 (0.54) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL8560666 | 0.84 | AGTR2 (0.54) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL10108979 | 0.84 | AGTR1 (0.66) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL7008517 | 0.84 | AGTR1 (0.49) | AGTR2AGTR1PPARGAGT | |
| SCHEMBL1653579 | 0.84 | AGTR2 (0.57) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL166867 | 0.83 | AGTR2 (0.56) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL3429149 | 0.83 | AGTR1 (0.57) | AGTR2AGTR1CYP3A4ADORA3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668272-B1 | A process for the production of tetrazolyl compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5763619-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS OR STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5578733-A | REACTION WITH MINERAL ACID IN THE PRESENCE OF ALCOHOL TO REMOVE PROTECTIVE GROUP | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0668272-A2 | A process for the production of tetrazolyl compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |