Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775547 | 0.80 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL6781524 | 0.77 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL6775111 | 0.73 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL8113017 | 0.69 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL8112895 | 0.68 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL821901 | 0.66 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL6774526 | 0.65 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL6781165 | 0.64 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL6773376 | 0.63 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL6780634 | 0.63 | CRHR1 (0.45) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920318-A4 | ARYLOXY- AND ARYLTHIOSUBSTITUTED PYRIMIDINES AND TRIAZINES AND DERIVATIVES THEREOF | DU PONT PHARM CO (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0920318-A1 | ARYLOXY- AND ARYLTHIOSUBSTITUTED PYRIMIDINES AND TRIAZINES AND DERIVATIVES THEREOF | Du Pont Pharmaceuticals Company (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997035580-A1 | ARYLOXY- AND ARYLTHIOSUBSTITUTED PYRIMIDINES AND TRIAZINES AND DERIVATIVES THEREOF | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |