Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 15/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773376 | 0.77 | CRHR1 (0.51) | CRHR1MEN1KMT2AGLAHTT | |
| SCHEMBL6780634 | 0.77 | CRHR1 (0.45) | CRHR1MEN1KMT2AGLAHTT | |
| SCHEMBL8107782 | 0.72 | MEN1 (0.46) | CRHR1MEN1KMT2AHTT | |
| SCHEMBL6775547 | 0.71 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL6775111 | 0.70 | CRHR1 (0.41) | CRHR1MEN1KMT2A | |
| SCHEMBL8112971 | 0.69 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL6774526 | 0.67 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL943918 | 0.66 | CA2 (0.41) | HTT | |
| SCHEMBL6774956 | 0.66 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL6775942 | 0.66 | CRHR1 (0.42) | CRHR1KMT2AGLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920318-A4 | ARYLOXY- AND ARYLTHIOSUBSTITUTED PYRIMIDINES AND TRIAZINES AND DERIVATIVES THEREOF | DU PONT PHARM CO (US) | 2000-03-15 | — | — | EP | claimed |
| EP-0920318-A1 | ARYLOXY- AND ARYLTHIOSUBSTITUTED PYRIMIDINES AND TRIAZINES AND DERIVATIVES THEREOF | Du Pont Pharmaceuticals Company (US) | 1999-06-09 | — | — | EP | claimed |
| WO-1997035580-A1 | ARYLOXY- AND ARYLTHIOSUBSTITUTED PYRIMIDINES AND TRIAZINES AND DERIVATIVES THEREOF | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | claimed |