Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119181 | 0.88 | HRH4 (0.61) | TDP1LMNAHRH4HRH3SMN1; SMN2 | |
| SCHEMBL7974364 | 0.84 | HDAC1 (0.49) | TDP1SMN1; SMN2NPC1RAB9AALOX5 | |
| SCHEMBL7961411 | 0.83 | CHRNB2 (0.52) | LMNAHRH4HRH3SMN1; SMN2NPC1 | |
| SCHEMBL7977081 | 0.81 | HRH3 (0.49) | LMNAHRH4HRH3SMN1; SMN2NPC1 | |
| SCHEMBL8104619 | 0.81 | HRH4 (0.54) | TDP1HRH4HRH3FFAR1ALDH1A1 | |
| SCHEMBL7960978 | 0.81 | HRH3 (0.47) | LMNAHRH4HRH3KMT2AMEN1 | |
| SCHEMBL7974350 | 0.80 | NPC1 (0.46) | HRH3SMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL12446326 | 0.79 | TDP1 (0.72) | TDP1LMNASMN1; SMN2FFAR1NPC1 | |
| SCHEMBL31657266 | 0.79 | TDP1 (0.72) | TDP1LMNASMN1; SMN2FFAR1NPC1 | |
| SCHEMBL13997917 | 0.79 | TDP1 (0.72) | TDP1LMNASMN1; SMN2FFAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597088-B1 | NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | INST NAT SANTE RECH MED (FR) | 2000-12-06 | — | — | EP | claimed |