Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119181 | 0.94 | HRH4 (0.61) | HRH4HRH3TDP1FFAR1CYP4F2 | |
| SCHEMBL8107511 | 0.89 | HRH4 (0.46) | HRH4HRH3ALDH1A1 | |
| SCHEMBL8113271 | 0.81 | TDP1 (0.50) | HRH4HRH3TDP1FFAR1ALDH1A1 | |
| SCHEMBL8119207 | 0.81 | TDP1 (0.40) | HRH4HRH3TDP1ALDH1A1 | |
| SCHEMBL7974587 | 0.79 | NPC1 (0.46) | — | |
| SCHEMBL4378585 | 0.78 | ALDH1A1 (0.53) | HRH3FFAR1ALDH1A1 | |
| SCHEMBL14027508 | 0.77 | SPHK2 (0.34) | HRH4HRH3APP | |
| Iodoproxyfan SCHEMBL3089477 | 0.77 | HRH3 (0.56) | HRH4HRH3APP | |
| SCHEMBL18381260 | 0.77 | NPC1 (0.39) | HRH4HRH3TDP1ALDH1A1 | |
| SCHEMBL5157531 | 0.75 | NAAA (0.35) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597088-B1 | NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | INST NAT SANTE RECH MED (FR) | 2000-12-06 | — | — | EP | claimed |