Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267594 | 0.91 | PRKCA (0.34) | PRKCAPRKCD | |
| SCHEMBL19546012 | 0.88 | PRKCA (0.33) | PRKCAPRKCD | |
| Methoxymethane SCHEMBL2475593 | 0.86 | PRKCA (0.32) | PRKCAPRKCD | |
| Ethylene Glycol SCHEMBL3723187 | 0.81 | PRKCA (0.38) | PRKCAPRKCD | |
| SCHEMBL27532678 | 0.79 | TSHR (0.40) | PRKCAPRKCD | |
| SCHEMBL28556969 | 0.79 | PRKCA (0.30) | PRKCAPRKCD | |
| SCHEMBL430876 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL10309264 | 0.78 | TSHR (0.32) | PRKCAPRKCD | |
| SCHEMBL24591676 | 0.76 | PRKCA (0.31) | PRKCAPRKCD | |
| SCHEMBL22488595 | 0.76 | PRKCA (0.31) | PRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404951-B1 | Polymerizable siloxane-quaternary amine copolymers | BAUSCH & LOMB (US) | 2013-09-11 | — | — | EP | disclosed |
| EP-2035486-B1 | POLYMERIZABLE SILOXANE-QUATERNARY AMINE COPOLYMERS | BAUSCH & LOMB (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2404951-A1 | Polymerizable siloxane-quaternary amine copolymers | BAUSCH & LOMB INCORPORATED (US) | 2012-01-11 | — | — | EP | disclosed |
| US-20090143556-A1 | Polymerizable siloxane-quaternary amine copolymers | BAUSCH & LOMB INCORPORATED (US) | 2009-06-04 | — | — | US | disclosed |
| EP-2035486-A1 | POLYMERIZABLE SILOXANE-QUATERNARY AMINE COPOLYMERS | Bausch & Lomb Incorporated (US) | 2009-03-18 | — | — | EP | disclosed |
| US-7468397-B2 | Polymerizable siloxane-quaternary amine copolymers | BAUSCH & LOMB INCORPORATED (US) | 2008-12-23 | — | — | US | disclosed |
| WO-2008005644-A1 | POLYMERIZABLE SILOXANE-QUATERNARY AMINE COPOLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20080001318-A1 | Polymerizable siloxane-quaternary amine copolymers | VALEANT PHARMACEUTICALS NORTH AMERICA LLC | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080001318-A1 | Polymerizable siloxane-quaternary amine copolymers | SRM, PARG, PARN | PRKCA 3907/4885PRKCD 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.