Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17200276 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6498288 | 0.91 | — | — | |
| Bromide SCHEMBL2760796 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL15901062 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL6360358 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL1032951 | 0.91 | — | — | |
| Bromide SCHEMBL17200272 | 0.91 | — | — | |
| SCHEMBL11615697 | 0.91 | — | — | |
| SCHEMBL1153 | 0.91 | — | — | |
| SCHEMBL5306546 | 0.91 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084841-A | Synthesis method of high-purity delta-lactone | 江西香海生物科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116354995-A | Boron-containing chiral allyl ester compound and high-stereoselectivity synthesis method | 武汉大学 | 2023-06-30 | — | — | CN | claimed |
| CN-111454150-B | Synthesis method of (S) -2-aryl propionate compound | 南京工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115772133-A | Preparation method of bis-ethylhexyloxyphenol methoxyphenyl triazine | 安徽英特美科技有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-111423299-B | Photochemical catalytic synthesis method of aryl olefin compound | 北京工商大学 | 2023-03-10 | — | — | CN | claimed |
| CN-115536572-A | Sulfonyl hydrazide compound and preparation method and application thereof | 中国科学技术大学 | 2022-12-30 | — | — | CN | claimed |
| CN-111423331-B | Photochemical catalytic synthesis method of aryl alkyl ether | 北京工商大学 | 2022-11-11 | — | — | CN | claimed |
| CN-111039822-B | Photochemical catalytic synthesis method of aromatic azo compound | 北京工商大学 | 2022-11-11 | — | — | CN | claimed |
| CN-114805170-A | Preparation method of novel silodosin chiral intermediate | 四川青木制药有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-110256205-B | Method for removing olefin protective group by nickel catalysis | 常熟理工学院 | 2022-02-11 | — | — | CN | claimed |
| CN-113666862-A | Method for preparing chiral 3-nitroindole compound by nickel-catalyzed asymmetric nitration reaction | 山东大学 | 2021-11-19 | — | — | CN | claimed |
| CN-109096149-B | Process for the preparation of beta-arylamines | 富兰克科技（深圳）股份有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-111454150-A | Synthesis method of (S) -2-aryl propionate compound | 南京工业大学 | 2020-07-28 | — | — | CN | claimed |
| US-5221774-A | Catalyst system containing nickel chloride, phosphine compound zinc and fluorinated organoacid | PHILLIPS PETROLEUM COMPANY (US) | 1993-06-22 | — | — | US | claimed |
| US-12042495-B2 | MAP4K1 inhibitors | BLUEPRINT MEDICINES CORPORATION (US) | 2024-07-23 | — | — | US | disclosed |
| US-12037324-B2 | Biarylmethyl heterocycles | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118251389-A | Pyridyl derivatives as sodium channel activators | 泽农医药公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-0248643-B1 | [Hexakis(Pentenenitrilo)nickel II]bis-[u-(Cyano)bis(triphenylborane)(I)], its method of preparation and its use | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| US-4749801-A | HYDROCYANATION PROMOTER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| EP-0248643-A2 | [Hexakis(Pentenenitrilo)nickel II]bis-[u-(Cyano)bis(triphenylborane)(I)], its method of preparation and its use | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |