Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113470 | 1.00 | TBXAS1 (0.42) | TBXAS1TYMPS1PR3S1PR2S1PR4 | |
| SCHEMBL8118310 | 1.00 | TBXAS1 (0.42) | TBXAS1TYMPS1PR3S1PR2S1PR4 | |
| SCHEMBL5720397 | 0.82 | GSK3A (0.39) | POLBRECQLSMN1; SMN2FAAHGSK3A | |
| SCHEMBL8112684 | 0.82 | RECQL (0.35) | POLBRECQLSMN1; SMN2FAAHGSK3A | |
| SCHEMBL5720115 | 0.82 | PSEN1 (0.39) | TBXAS1POLBRECQLSMN1; SMN2FAAH | |
| SCHEMBL11124513 | 0.82 | PTGIR (0.49) | TBXAS1FAAHMAPT | |
| SCHEMBL8111700 | 0.82 | PTGIR (0.49) | TBXAS1FAAHMAPT | |
| SCHEMBL8104133 | 0.82 | PTGIR (0.49) | TBXAS1FAAHMAPT | |
| SCHEMBL8103785 | 0.82 | PTGIR (0.49) | TBXAS1FAAHMAPT | |
| Phosphoric Acid SCHEMBL8029423 | 0.81 | FAAH (0.44) | POLBRECQLSMN1; SMN2FAAHGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626969-B1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2000-05-24 | — | — | EP | claimed |