Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.60 |
| ▸ | HTR1A | P08908 | 7/20 | 0.59 |
| ▸ | HTR2C | P28335 | 5/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116685 | 0.91 | SIGMAR1 (0.62) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9556394 | 0.90 | SIGMAR1 (0.61) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437751 | 0.88 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437827 | 0.86 | SIGMAR1 (0.49) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437780 | 0.85 | SIGMAR1 (0.53) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437711 | 0.85 | SIGMAR1 (0.53) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437912 | 0.85 | SIGMAR1 (0.56) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437702 | 0.85 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437923 | 0.84 | SIGMAR1 (0.47) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437813 | 0.83 | MAOB (0.47) | SIGMAR1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | disclosed |
| CN-1055924-C | Novel aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 2000-08-30 | — | — | CN | disclosed |
| US-5688820-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| US-5688811-A | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| US-5534511-A | AFFINITY FOR SIGMA RECEPTORS, ANTIINFLAMMATORY, TREATMENT OF ARTHRITIS | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| CN-1112114-A | Novel aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-22 | — | — | CN | disclosed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |