Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | ACHE | P22303 | 7/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437827 | 0.97 | SIGMAR1 (0.49) | SIGMAR1ACHEHTR1AHTR2C | |
| SCHEMBL9437912 | 0.96 | SIGMAR1 (0.56) | SIGMAR1ACHEHTR1AHTR2C | |
| SCHEMBL9437780 | 0.94 | SIGMAR1 (0.53) | SIGMAR1ACHEHTR1AHTR2C | |
| SCHEMBL9437751 | 0.92 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437711 | 0.92 | SIGMAR1 (0.53) | SIGMAR1ACHEHTR1AHTR2C | |
| SCHEMBL8116685 | 0.89 | SIGMAR1 (0.62) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9556394 | 0.88 | SIGMAR1 (0.61) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8114155 | 0.85 | SIGMAR1 (0.60) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437691 | 0.82 | SIGMAR1 (0.49) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437932 | 0.81 | SIGMAR1 (0.49) | SIGMAR1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |