SCHEMBL811477

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL810621	0.87	CYP2D6 (0.43)	MAPTKDM4EALDH1A1HPGDLMNA
	SCHEMBL810257	0.87	MAPT (0.42)	MAPTKDM4EALDH1A1HPGDLMNA
	SCHEMBL810228	0.82	HTT (0.44)	MAPTALDH1A1HPGDLMNANPSR1
	SCHEMBL810189	0.81	MAPT (0.50)	MAPTKDM4EALDH1A1HPGDLMNA
	SCHEMBL810088	0.76	MAOB (0.52)	ALDH1A1
	SCHEMBL4973845	0.73	SIRT2 (0.41)	SLC6A4SLC6A2
	SCHEMBL810973	0.73	NR1H2 (0.45)	MAPTKDM4EALDH1A1HPGDLMNA
	SCHEMBL810611	0.73	PIM1 (0.51)	MITF
	SCHEMBL810394	0.71	MAOB (0.52)	ALDH1A1
	SCHEMBL810140	0.69	MAOB (0.46)	LMNASLC6A4SLC6A2CYP2C19SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.