SCHEMBL810228

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL809916	0.89	MAPT (0.46)	HTTMEN1KMT2AALDH1A1MAPT
	SCHEMBL811477	0.82	MAPT (0.36)	MEN1KMT2AALDH1A1MAPTLMNA
	SCHEMBL811556	0.78	PDE7A (0.53)	HTTMEN1KMT2AALDH1A1MAPT
	SCHEMBL811476	0.77	MAPT (0.43)	HTTMEN1KMT2AALDH1A1MAPT
	SCHEMBL810343	0.76	MAPT (0.50)	HTTMEN1KMT2AALDH1A1MAPT
	SCHEMBL5064335	0.76	MAPT (0.41)	HTTMEN1KMT2AALDH1A1MAPT
	SCHEMBL811151	0.74	MAPT (0.48)	MEN1KMT2AALDH1A1MAPTSMN1; SMN2
	SCHEMBL811427	0.72	HTT (0.48)	HTTMEN1KMT2AALDH1A1MAPT
	SCHEMBL1454766	0.71	PDE7A (0.55)	HTTMEN1KMT2AALDH1A1MAPT
	SCHEMBL20526922	0.71	FFAR1 (0.44)	ALDH1A1MAPTSMN1; SMN2LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.