Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | NMT2 | O60551 | 2/20 | 0.45 |
| ▸ | NMT1 | P30419 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116780 | 0.91 | AKR1B1 (0.53) | MAOBAKR1B1GPR35SLC2A1NMT2 | |
| SCHEMBL8123931 | 0.89 | GPR35 (0.52) | MAOBGPR35LOXL2CNR2CYP2A6 | |
| SCHEMBL11533313 | 0.87 | MAOB (0.48) | MAOBAKR1B1GPR35SLC2A1NMT2 | |
| SCHEMBL7553333 | 0.86 | AKR1B1 (0.53) | MAOBAKR1B1GPR35SLC2A1TP53 | |
| SCHEMBL8113760 | 0.85 | GPR35 (0.50) | MAOBGPR35LOXL2CNR2CYP2A6 | |
| SCHEMBL8106509 | 0.82 | AKR1B1 (0.56) | MAOBAKR1B1GPR35SLC2A1TP53 | |
| SCHEMBL8117084 | 0.81 | GPR35 (0.47) | MAOBGPR35LOXL2TP53THRB | |
| SCHEMBL7633152 | 0.81 | AKR1B1 (0.59) | MAOBAKR1B1GPR35SLC2A1LOXL2 | |
| SCHEMBL22617428 | 0.81 | MAOB (0.61) | MAOBAKR1B1GPR35SLC2A1TP53 | |
| SCHEMBL8827768 | 0.81 | AKR1B1 (0.55) | MAOBAKR1B1GPR35SLC2A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |