Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116101 | 0.88 | AKR1B1 (0.55) | AKR1B1KMT2APOLBMAOBKDM4E | |
| SCHEMBL8123206 | 0.83 | AKR1B1 (0.72) | AKR1B1KMT2APOLBMAOBKDM4E | |
| SCHEMBL8106900 | 0.78 | POLB (0.62) | AKR1B1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL8115562 | 0.78 | PRKDC (0.56) | AKR1B1KMT2AMAOBKDM4EALDH1A1 | |
| SCHEMBL8115968 | 0.77 | SLC2A1 (0.60) | AKR1B1POLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29355363 | 0.77 | ALDH1A1 (0.60) | AKR1B1KMT2APOLBMAOBKDM4E | |
| SCHEMBL5188789 | 0.76 | AKR1B1 (0.76) | AKR1B1KMT2AMAOBKDM4EALDH1A1 | |
| SCHEMBL30225130 | 0.76 | AKR1B1 (0.76) | AKR1B1KMT2AMAOBKDM4EALDH1A1 | |
| SCHEMBL30643073 | 0.76 | POLB (0.62) | KMT2APOLBMAOBALDH1A1MEN1 | |
| SCHEMBL30224951 | 0.75 | MAOB (0.53) | AKR1B1KMT2AMAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |