Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.43 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121356 | 0.83 | QPCT (0.59) | NOTUMMAPKAPK2QPCTELAVL1PTGS2 | |
| SCHEMBL8116989 | 0.80 | QPCT (0.59) | NOTUMMAPKAPK2QPCTELAVL1POLH | |
| SCHEMBL6958354 | 0.78 | CA12 (0.55) | NOTUMPTGS2MIF | |
| SCHEMBL6172775 | 0.77 | SMN1; SMN2 (0.54) | PTGS2POLHCYP3A4MEN1GLA | |
| SCHEMBL8115383 | 0.76 | CSNK2A2 (0.57) | ELAVL1POLHMEN1KMT2AALDH1A1 | |
| SCHEMBL17128868 | 0.76 | MAPT (0.46) | NOTUMCYP3A4MEN1GLAKMT2A | |
| SCHEMBL6827354 | 0.76 | CYP3A4 (0.60) | NOTUMMIFCYP3A4MEN1KMT2A | |
| SCHEMBL8105644 | 0.72 | MAPKAPK2 (0.46) | MAPKAPK2QPCTELAVL1CYP3A4MEN1 | |
| SCHEMBL13006310 | 0.71 | HSD17B1 (0.58) | BCL2PTGS2CYP3A4FGFR1CYP2C9 | |
| SCHEMBL29369936 | 0.70 | CYP3A4 (0.50) | MAPKAPK2ELAVL1PTGS2POLHCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |