Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109864 | 0.80 | ATM (0.54) | HSD17B3SLC9A1MEN1KMT2ACYP3A4 | |
| SCHEMBL1008973 | 0.78 | MEN1 (0.60) | MEN1KMT2AHPGDGABRA1GABRB2 | |
| SCHEMBL6827384 | 0.77 | ALDH1A1 (0.60) | SLC9A1MEN1KMT2ACYP3A4GLA | |
| SCHEMBL8107451 | 0.77 | MAOB (0.49) | MEN1KMT2ACYP3A4GLAELAVL1 | |
| SCHEMBL30568046 | 0.74 | SHBG (0.51) | HSD17B3MEN1KMT2AHPGDTP53 | |
| SCHEMBL20473368 | 0.74 | SHBG (0.51) | HSD17B3MEN1KMT2AHPGDTP53 | |
| SCHEMBL17128801 | 0.74 | MEN1 (0.43) | HSD17B3MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL27806529 | 0.74 | HPGD (0.67) | MEN1KMT2ACYP3A4GLAHPGD | |
| SCHEMBL29129672 | 0.73 | MAPT (0.55) | MEN1KMT2ACYP3A4HPGDGABRA1 | |
| SCHEMBL8121356 | 0.72 | QPCT (0.59) | MAPKAPK2HSD17B3MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |