Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.70 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8824041 | 0.99 | ITGB3 (0.69) | ITGB3ITGA2BENPP2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8824131 | 0.99 | ITGB3 (0.69) | ITGB3ITGA2BENPP2NPC1RAB9A | |
| SCHEMBL8121157 | 0.87 | ITGB3 (0.63) | ITGB3ITGA2BENPP2SCN9A | |
| SCHEMBL8121166 | 0.86 | ITGB3 (0.62) | ITGB3ITGA2BENPP2CXCR3SCN9A | |
| SCHEMBL8107316 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2BENPP2NPC1RAB9A | |
| SCHEMBL8824070 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BENPP2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8824031 | 0.82 | ITGB3 (0.98) | ITGB3ITGA2BENPP2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8824115 | 0.82 | ITGB3 (0.98) | ITGB3ITGA2BENPP2NPC1RAB9A | |
| SCHEMBL8118461 | 0.81 | ITGB3 (0.71) | ITGB3ITGA2BENPP2NPC1RAB9A | |
| SCHEMBL8124324 | 0.79 | ITGB3 (0.71) | ITGB3ITGA2BENPP2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719775-B1 | Substituted 4-phenyl thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2000-07-12 | — | — | EP | claimed |
| US-5607952-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, ATHEROSCLEROSIS AND ANTIDIABETIC AGENTS | SANOFI (FR) | 1997-03-04 | — | — | US | claimed |
| EP-0719775-A1 | Substituted 4-phenyl thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-07-03 | — | — | EP | claimed |
| JP-8231542-A | — | — | None | — | — | JP | disclosed |
| EP-0719775-B1 | Substituted 4-phenyl thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2000-07-12 | — | — | EP | disclosed |
| US-5607952-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, ATHEROSCLEROSIS AND ANTIDIABETIC AGENTS | SANOFI (FR) | 1997-03-04 | — | — | US | disclosed |
| JP-H08231542-A | SUBSTITUTED 4-PHENYLTHIAZOLE DERIVATIVE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SANOFI SA | 1996-09-10 | — | — | JP | disclosed |
| EP-0719775-A1 | Substituted 4-phenyl thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-07-03 | — | — | EP | disclosed |