Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824067 | 0.83 | ITGB3 (0.69) | ITGB3ITGA2BNPY5RENPP2RAB9A | |
| SCHEMBL8115443 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BENPP2KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL8824131 | 0.81 | ITGB3 (0.69) | ITGB3ITGA2BENPP2KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL8824041 | 0.81 | ITGB3 (0.69) | ITGB3ITGA2BENPP2KMT2ARAB9A | |
| SCHEMBL27330557 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2BMAPTMEN1KMT2A | |
| SCHEMBL27318569 | 0.73 | ITGB3 (0.68) | ITGB3ITGA2BNPY5RENPP2RAB9A | |
| SCHEMBL8121166 | 0.73 | ITGB3 (0.62) | ITGB3ITGA2BENPP2MAPTMEN1 | |
| SCHEMBL27336936 | 0.72 | ITGB3 (0.66) | ITGB3ITGA2BNPY5RENPP2RAB9A | |
| SCHEMBL8121157 | 0.71 | ITGB3 (0.63) | ITGB3ITGA2BENPP2 | |
| SCHEMBL1474528 | 0.66 | RAB9A (0.60) | ITGB3ITGA2BNPY5RMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1133289-A | Substituted 4-phenyl thiazole derivant, preparation and medicine compositions thereof | SANOFI SA (FR) | 1996-10-16 | — | — | CN | claimed |
| CN-1048726-C | Substituted 4-phenyl thiazole derivant, preparation and medicine compositions thereof | SANOFI SA (FR) | 2000-01-26 | — | — | CN | disclosed |
| US-5607952-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, ATHEROSCLEROSIS AND ANTIDIABETIC AGENTS | SANOFI (FR) | 1997-03-04 | — | — | US | disclosed |
| CN-1133289-A | Substituted 4-phenyl thiazole derivant, preparation and medicine compositions thereof | SANOFI SA (FR) | 1996-10-16 | — | — | CN | disclosed |