Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265371 | 0.73 | IDO1 (0.45) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL8115480 | 0.73 | CA12 (0.42) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL29002710 | 0.71 | SMN1; SMN2 (0.45) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL8115606 | 0.71 | GLA (0.49) | ALDH1A1MEN1KMT2AMAPTCMA1 | |
| SCHEMBL15457854 | 0.70 | IDO1 (0.44) | ALDH1A1MEN1KMT2AIDO1GAA | |
| SCHEMBL10462019 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2IDO1 | |
| SCHEMBL14240274 | 0.69 | IDO1 (0.40) | ALDH1A1MEN1KMT2AMAPTCMA1 | |
| SCHEMBL2628877 | 0.69 | CMA1 (0.56) | ALDH1A1MEN1KMT2AMAPTCMA1 | |
| SCHEMBL11092391 | 0.69 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTCMA1 | |
| SCHEMBL5443745 | 0.68 | MMP2 (0.70) | CMA1NPSR1SMN1; SMN2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |