Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115691 | 1.00 | FUT8 (0.70) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL12442261 | 0.92 | FUT8 (0.65) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL12138276 | 0.91 | FUT8 (0.69) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL8974959 | 0.91 | FUT8 (0.69) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL13991393 | 0.90 | FUT8 (0.62) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL18218275 | 0.90 | FUT8 (0.66) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL12646747 | 0.90 | FUT8 (0.62) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL12646578 | 0.88 | FUT8 (0.57) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL12974316 | 0.88 | FUT8 (0.57) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 | |
| SCHEMBL13111196 | 0.88 | FUT8 (0.64) | FUT8CYP1A2MAPK1CYP2C9DNASE1L3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254789-B2 | Ionically modified silicones, compositions, and medical devices formed therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2022-02-22 | — | — | US | disclosed |
| EP-3583176-B1 | IONICALLY MODIFIED SILICONES, COMPOSITIONS, AND MEDICAL DEVICES FORMED THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2020-12-16 | — | — | EP | disclosed |
| US-20200223985-A1 | IONICALLY MODIFIED SILICONES, COMPOSITIONS, AND MEDICAL DEVICES FORMED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2020-07-16 | — | — | US | disclosed |
| WO-2018152392-A1 | IONICALLY MODIFIED SILICONES, COMPOSITIONS, AND MEDICAL DEVICES FORMED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-08-23 | — | — | WO | disclosed |
| US-7442780-B2 | light fastness, wet and dry crock resistance, perspiration, dye-transfer staining and wash fastness | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-10-28 | — | — | US | disclosed |
| EP-0576143-B1 | Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine-4-ylamino group | BASF AG (DE) | 2000-08-09 | — | — | EP | disclosed |
| EP-0559310-B1 | Ink compositions | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| EP-0372729-B1 | Reactive dyes | ZENECA LTD (GB) | 1995-01-18 | — | — | EP | disclosed |
| US-5373094-A | Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine group | ZENECA LIMITED (GB) | 1994-12-13 | — | — | US | disclosed |
| EP-0576143-A2 | Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine-4-ylamino group | ZENECA LIMITED (GB) | 1993-12-29 | — | — | EP | disclosed |
| US-5269816-A | Water-soluble reactive triazine dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| EP-0559310-A1 | Ink compositions | ZENECA LIMITED (GB) | 1993-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254789-B2 | Ionically modified silicones, compositions, and medical devices formed therefrom | ORMDL3, THEM6, ITK | FUT8 1837/4885CYP1A2 4732/4885MAPK1 1107/4885 |
| US-20200223985-A1 | IONICALLY MODIFIED SILICONES, COMPOSITIONS, AND MEDICAL DEVICES FORMED THEREFROM | ORMDL3, THEM6, ITK | FUT8 1837/4885CYP1A2 4732/4885MAPK1 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.