Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27604883 | 0.91 | KMT2A (0.41) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL26751106 | 0.88 | BCHE (0.46) | ALDH1A1KMT2AEPHX2TDP1BCHE | |
| SCHEMBL29523808 | 0.87 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KMT2AMEN1EPHX2 | |
| SCHEMBL11046760 | 0.85 | NAAA (0.52) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL24246694 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL11043206 | 0.83 | NAAA (0.51) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL20859045 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL18686104 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1EPHX2EPHX1 | |
| SCHEMBL26651242 | 0.80 | MEN1 (0.48) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6181708 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632036-B1 | Amide derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses | SANKYO CO (JP) | 2000-03-01 | — | — | EP | disclosed |
| US-5614550-A | ANTICHOLESTEROL AGENTS OR ARTERIOSCLEROSIS AGENTS FOR HUMANS | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5534529-A | Substituted aromatic amides and ureas derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0632036-A2 | Amide and urea derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1995-01-04 | — | — | EP | disclosed |