Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 12/20 | 0.46 |
| ▸ | EDNRA | P25101 | 12/20 | 0.46 |
| ▸ | PTGES | O14684 | 6/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109239 | 0.84 | EDNRB (0.57) | EDNRBEDNRA | |
| SCHEMBL9046722 | 0.82 | EDNRB (0.40) | EDNRBEDNRAPTGESALOX5PPARG | |
| SCHEMBL7937196 | 0.82 | EDNRB (0.49) | EDNRBEDNRA | |
| SCHEMBL8200442 | 0.80 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL1069539 | 0.79 | EDNRB (0.55) | EDNRBEDNRA | |
| SCHEMBL7934306 | 0.76 | EDNRB (0.46) | EDNRBEDNRA | |
| SCHEMBL8100747 | 0.75 | EDNRB (0.67) | EDNRBEDNRA | |
| SCHEMBL8098308 | 0.75 | EDNRB (0.50) | EDNRBEDNRA | |
| SCHEMBL9408612 | 0.74 | EDNRB (0.45) | EDNRBEDNRAPTGESALOX5PPARG | |
| SCHEMBL8109266 | 0.73 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030975-A | ANTAGONIST OF ENDOTHELINS, I.E. INHIBITION OF BINDING WITH RECEPTOR; ANTITUMOR AND -CARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0969841-A1 | USE OF CARBOXYLIC ACID DERIVATIVES FOR TREATING CANCER | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998041206-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE IN TREATING CANCER | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-24 | — | — | WO | disclosed |
| US-5703017-A | HERBICIDES, PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |