Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.44 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794104 | 0.85 | CA12 (0.50) | CA9CA12CA1PIM1ALDH1A1 | |
| SCHEMBL5114485 | 0.82 | CA9 (0.60) | CA9CA12CA1PIM1ALDH1A1 | |
| SCHEMBL24753975 | 0.82 | CA12 (0.56) | CA9CA12CA1PIM1ALDH1A1 | |
| SCHEMBL5342252 | 0.78 | CA9 (0.55) | CA9CA12CA1PIM1ALDH1A1 | |
| SCHEMBL5346812 | 0.78 | ALDH1A1 (0.59) | CA9CA12CA1ALDH1A1KDM4E | |
| SCHEMBL3910257 | 0.78 | CA9 (0.55) | CA9CA12CA1PIM1ALDH1A1 | |
| SCHEMBL8114895 | 0.78 | CA9 (0.55) | CA9CA12CA1PIM1ALDH1A1 | |
| SCHEMBL25607742 | 0.76 | CA9 (0.62) | CA9CA12CA1PIM1ALDH1A1 | |
| SCHEMBL8105516 | 0.74 | CA9 (0.50) | CA9CA12CA1PIM1ALDH1A1 | |
| SCHEMBL8114801 | 0.74 | CA9 (0.50) | CA9CA12CA1PIM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |