SCHEMBL5114485

SCHEMBL5114485

O=c1cc(O)c2c(O)cccc2o1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 2/20 0.60
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
MAOA P21397 2/20 0.52
CYP3A4 P08684 6/20 0.50
AR P10275 6/20 0.50
KMT2A Q03164 5/20 0.50
MAPT P10636 5/20 0.50
MEN1 O00255 4/20 0.50
ALDH1A1 P00352 3/20 0.50
ALOX15 P16050 3/20 0.50
EGFR P00533 1/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1A2 P05177 1/20 0.50
PKM P14618 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CYP1B1 Q16678 1/20 0.50
FTO Q9C0B1 1/20 0.50
MAPK1 P28482 3/20 0.49
HPGD P15428 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10847397 0.84 MEN1 (0.54) CA9CA12CA1MAOACYP3A4
SCHEMBL10848826 0.82 AR (0.50) CA9CA12CA1MAOACYP3A4
SCHEMBL8114895 0.82 CA9 (0.55) CA9CA12CA1MAOACYP3A4
SCHEMBL4930754 0.82 ALDH1A1 (0.64) CA9CA12CA1MAOACYP3A4
SCHEMBL5346812 0.82 ALDH1A1 (0.59) CA9CA12CA1CYP3A4KMT2A
SCHEMBL10794104 0.82 CA12 (0.50) CA9CA12CA1MAOACYP3A4
SCHEMBL3910257 0.82 CA9 (0.55) CA9CA12CA1MAOACYP3A4
SCHEMBL5342252 0.82 CA9 (0.55) CA9CA12CA1CYP3A4AR
SCHEMBL8117166 0.82 CA9 (0.55) CA9CA12CA1MAOACYP3A4
SCHEMBL9160367 0.80 ALDH1A1 (0.64) CA9CA12CA1MAOAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4317284-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE Daikin Industries, Ltd. (JP) 2024-02-07 EP disclosed
US-20240034856-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2024-02-01 US disclosed
CN-117043260-A Composition for cross-linking fluororubber and molded article 大金工业株式会社 2023-11-10 CN disclosed
WO-2022210044-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE ダイキン工業株式会社 2022-10-06 WO disclosed
EP-3848367-A1 TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2021-07-14 EP disclosed
US-7384975-B2 Substituted furochromenes, preparation thereof and their antiinflammatory action GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) 2008-06-10 US disclosed
US-7208518-B2 Substituted furochromene compounds of antiinflammatory action GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) 2007-04-24 US disclosed
CN-1839138-A Substituted furochromene compounds with anti-inflammatory action PLIVA ISTRAZIVACKI INST D O O (HR) 2006-09-27 CN disclosed
CN-1839137-A Substituted furochromenes, preparation thereof and their antiinflammatory action PLIVA ISTRAZIVACKI INST D O O (HR) 2006-09-27 CN disclosed
US-20060148890-A1 Substituted furochromene compounds of antiinflammatory action PLIVA-LSTRAZIVACKI INSTITUT D.O.O. (HR) 2006-07-06 US disclosed
EP-0968202-B1 Process for preparing photoactive coumarin dervatives CLARIANT FINANCE BVI LTD (VG) 2002-07-03 EP disclosed
EP-0977747-B1 PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT FINANCE BVI LTD (VG) 2002-06-12 EP disclosed
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
CN-1254338-A Process for preparing photoactive coumarin derivatives HOECHST CELANESE CORP (CH) 2000-05-24 CN disclosed
EP-0977747-A1 PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT INTERNATIONAL LTD. (CH) 2000-02-09 EP disclosed
EP-0968202-A1 PROCESS FOR PREPARING PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT INTERNATIONAL LTD. (CH) 2000-01-05 EP disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed
WO-1998039317-A1 PROCESS FOR PREPARING PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT INTERNATIONAL LTD. (CH) 1998-09-11 WO disclosed
WO-1998039319-A1 PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT INTERNATIONAL LTD. (CH) 1998-09-11 WO disclosed
WO-1993003036-A1 BENZOPYRANO[4,3-c]PYRAZOLES, THEIR PREPARATION AND THEIR USE AS IMMUNOMODULATORS THE BOOTS COMPANY PLC (GB) 1993-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060148890-A1 Substituted furochromene compounds of antiinflammatory action LTC4S, CYP11B2, CYP11B1 CA9 2752/4885CA12 3303/4885CA1 1868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.