Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | SDHA | P31040 | 2/20 | 0.45 |
| ▸ | CALML3 | P27482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822101 | 0.83 | MAOA (0.63) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7657498 | 0.82 | MAOA (0.52) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL8102119 | 0.82 | MAOA (0.62) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL4753020 | 0.82 | MAOA (0.62) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL8117437 | 0.81 | MAOA (0.61) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL8110873 | 0.80 | MAOA (0.52) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL8822058 | 0.80 | MAOA (0.60) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL8101745 | 0.80 | MAOA (0.55) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL4752188 | 0.79 | MAOA (0.59) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL8111222 | 0.79 | MAOA (0.55) | MAOAMAOBPTGS1SDHACALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034175-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | AstraZeneca UK Limited (GB) | 2000-09-13 | — | — | EP | claimed |
| WO-1999028317-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | ASTRAZENECA UK LIMITED (GB) | 1999-06-10 | — | — | WO | claimed |