Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | SDHA | P31040 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CALML3 | P27482 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657494 | 0.84 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8117445 | 0.82 | MAOA (0.50) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7842939 | 0.82 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3755880 | 0.82 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7842942 | 0.82 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3754635 | 0.82 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8124484 | 0.81 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7651821 | 0.81 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7838549 | 0.81 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7838545 | 0.81 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495551-B1 | P-IMIDAZOLE-PHENYL-OXAZOLIDINES; EFFECTIVE AGAINST GRAMPOSITIVE BACTERIA | SYNGENTA LIMITED (GB) | 2002-12-17 | — | — | US | claimed |
| US-6495551-B1 | P-IMIDAZOLE-PHENYL-OXAZOLIDINES; EFFECTIVE AGAINST GRAMPOSITIVE BACTERIA | SYNGENTA LIMITED (GB) | 2002-12-17 | — | — | US | disclosed |
| EP-1034175-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | AstraZeneca UK Limited (GB) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999028317-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | ASTRAZENECA UK LIMITED (GB) | 1999-06-10 | — | — | WO | disclosed |