Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064447 | 0.95 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5971872 | 0.91 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5134387 | 0.91 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5059937 | 0.91 | LMNA (0.55) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5061374 | 0.86 | LMNA (0.57) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5060249 | 0.83 | CYP3A4 (0.57) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5064071 | 0.82 | LMNA (0.58) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5055631 | 0.82 | MRGPRX4 (0.61) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5060360 | 0.82 | MRGPRX4 (0.56) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 | |
| SCHEMBL5055860 | 0.82 | CYP3A4 (0.56) | ALDH1A1CYP3A4CYP2C9LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988292-A2 | PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056771-A2 | PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-17 | — | — | WO | disclosed |