Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499342 | 0.76 | NOS3 (0.58) | KMT2AMEN1NOX1ADRA2AADRA2B | |
| SCHEMBL24991972 | 0.75 | ALDH1A1 (0.53) | KMT2AMEN1KDM4EALDH1A1ALOX15 | |
| SCHEMBL13700870 | 0.75 | NOS3 (0.43) | KMT2AMEN1NOX1ADRA2AADRA2B | |
| SCHEMBL499173 | 0.74 | NOS3 (0.60) | DRD3MAPTRAD52GAAGFER | |
| SCHEMBL499645 | 0.74 | NOS3 (0.60) | KMT2AMEN1NOX1ADRA2AADRA2B | |
| SCHEMBL499955 | 0.73 | NOS3 (0.57) | ALDH1A1POLB | |
| SCHEMBL3969979 | 0.73 | NOTUM (0.56) | KMT2AL3MBTL1KDM4EALDH1A1ALOX15 | |
| SCHEMBL28585181 | 0.72 | MAPT (0.47) | KMT2AMEN1NOX1ADRA2AADRA2B | |
| SCHEMBL499065 | 0.72 | NOS3 (0.58) | DRD3ALDH1A1POLB | |
| SCHEMBL499358 | 0.71 | NOS3 (0.59) | KDM4EALDH1A1GFERPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049692-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | Bayer Aktiengesellschaft (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037641-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |