Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125197 | 0.89 | ALDH1A1 (0.37) | POLBALDH1A1P2RX7KMT2AMAPT | |
| SCHEMBL8118086 | 0.82 | ALDH1A1 (0.36) | POLBAKR1C3ALDH1A1P2RX7MAPK14 | |
| SCHEMBL8134613 | 0.81 | POLB (0.35) | POLBAKR1C3ALDH1A1P2RX7MAPK14 | |
| SCHEMBL7652778 | 0.80 | LMNA (0.40) | POLBAKR1C3ALDH1A1P2RX7MAPK14 | |
| SCHEMBL8119583 | 0.71 | ALDH1A1 (0.40) | POLBALDH1A1KMT2AMAPTNPSR1 | |
| SCHEMBL8127530 | 0.71 | ALDH1A1 (0.39) | ALDH1A1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL8133210 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL7652026 | 0.69 | AKR1C3 (0.40) | POLBAKR1C3ALDH1A1MAPK14KMT2A | |
| SCHEMBL7655761 | 0.69 | ALDH1A1 (0.42) | ALDH1A1P2RX7KMT2AMAPTNPSR1 | |
| SCHEMBL11417296 | 0.68 | ALDH1A1 (0.40) | POLBALDH1A1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160114-A | USEFUL FOR THE TREATMENT OF ATHEROSCLEROTIC CONDITIONS AND CORONARY HEART DISEASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-12-12 | — | — | US | disclosed |