Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 8/20 | 0.55 |
| ▸ | CASP7 | P55210 | 6/20 | 0.51 |
| ▸ | CASP1 | P29466 | 5/20 | 0.51 |
| ▸ | CASP9 | P55211 | 3/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | CASP4 | P49662 | 2/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840715 | 1.00 | CASP3 (0.55) | CASP3CASP7CASP1CASP9ELANE | |
| SCHEMBL20543505 | 0.96 | CASP3 (0.58) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL1264575 | 0.89 | CASP3 (0.55) | CASP3CASP7CASP1CASP9ELANE | |
| SCHEMBL614741 | 0.89 | CASP3 (0.62) | CASP3CASP7CASP1CASP9ELANE | |
| SCHEMBL3140616 | 0.89 | CASP3 (0.62) | CASP3CASP7CASP1CASP9ELANE | |
| SCHEMBL29409608 | 0.88 | CASP3 (0.55) | CASP3CASP7CASP1CASP9ELANE | |
| SCHEMBL18740358 | 0.88 | CASP3 (0.58) | CASP3CASP7CASP1CASP9ELANE | |
| SCHEMBL24213871 | 0.87 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL17494194 | 0.87 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL7112627 | 0.87 | CASP3 (0.58) | CASP3CASP7CASP1CASP9ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8652844-B2 | Methods for the cryopreservation of animal cells that contain high levels of intracellular lipids | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2014-02-18 | — | — | US | claimed |
| US-20100190248-A1 | Methods for the Cryopreservation of Animal Cells that Contain High Levels of Intracellular Lipids | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2010-07-29 | — | — | US | claimed |
| US-20090232866-A1 | Oligopeptides as coating material for medical products | HEMOTEQ AG (DE) | 2009-09-17 | — | — | US | claimed |
| WO-2007146253-A2 | METHODS FOR THE CRYOPRESERVATION OF ANIMAL CELLS THAT CONTAIN HIGH LEVELS OF INTRACELLULAR LIPIDS | CRITSER JOHN K (US) | 2007-12-21 | — | — | WO | claimed |
| JP-2007507264-A | — | — | 2007-03-29 | — | — | JP | claimed |
| EP-1670502-A2 | OLIGOPEPTIDES AS COATING MATERIAL FOR MEDICAL PRODUCTS | Hemoteq GmbH (DE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005039629-A2 | CASPASE INHIBITORS AS COATING MATERIEL FOR MEDICAL PRODUCTS FOR INHIBITING RESTENOSIS | HEMOTEQ GMBH (DE) | 2005-05-06 | — | — | WO | claimed |
| CN-115551536-A | Caspase inhibitors for enhanced wound repair and treatment of bacterial and viral infections | 约翰斯·霍普金斯大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-114057777-B | Beta-carboline derivative and preparation method and application thereof | 南方海洋科学与工程广东省实验室(湛江) | 2022-12-02 | — | — | CN | disclosed |
| CN-114057777-A | Beta-carboline derivative and preparation method and application thereof | 南方海洋科学与工程广东省实验室(湛江) | 2022-02-18 | — | — | CN | disclosed |
| EP-3242723-B1 | USE OF HINOKITIOL FOR RESTORING PHYSIOLOGY IN IRON-DEFICIENT ORGANISMS | UNIV ILLINOIS (US) | 2021-10-06 | — | — | EP | disclosed |
| US-10842843-B2 | Augmenting the immune response by promoting cell death of immune cells | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2020-11-24 | — | — | US | disclosed |
| US-10456441-B2 | Augmenting the immune response by promoting cell death of immune cells | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2019-10-29 | — | — | US | disclosed |
| US-20030108551-A1 | Methods and compositions of monoclonal antibodies specific for beta-amyloid proteins | DIAGENICS INTERNATIONAL CORPORATION | 2003-06-12 | — | — | US | disclosed |
| EP-1124842-B1 | BETULINIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROECTODERMAL TUMORS | DEUTSCHES KREBSFORSCH (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2003039467-A2 | MONOCLONAL ANTIBODIES SPECIFIC FOR BETA-AMYLOID. | DIAGENICS INTERNATIONAL CORPORATION (US) | 2003-05-15 | — | — | WO | disclosed |
| WO-2002074346-A2 | TARGETING CHEMICAL COMPOUNDS TO CELLS | NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) | 2002-09-26 | — | — | WO | disclosed |
| US-6369109-B1 | Betulinic acid and derivatives thereof useful for the treatment of neuroectodermal tumor | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2002-04-09 | — | — | US | disclosed |
| EP-1124842-A1 | BETULINIC ACID AND DERIVATIVES THEREOF USEFUL FOR THE TREATMENT OF NEUROECTODERMAL TUMORS | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024762-A1 | BETULINIC ACID AND DERIVATIVES THEREOF USEFUL FOR THE TREATMENT OF NEUROECTODERMAL TUMORS | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2000-05-04 | — | — | WO | disclosed |