Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 10/20 | 0.55 |
| ▸ | CASP7 | P55210 | 6/20 | 0.51 |
| ▸ | CASP1 | P29466 | 6/20 | 0.51 |
| ▸ | CASP9 | P55211 | 4/20 | 0.51 |
| ▸ | CASP4 | P49662 | 3/20 | 0.48 |
| ▸ | CASP10 | Q92851 | 3/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CASP5 | P51878 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4438547 | 0.93 | CTSK (0.50) | CASP3CASP1CTSK | |
| SCHEMBL811863 | 0.89 | CASP3 (0.55) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL28840715 | 0.89 | CASP3 (0.55) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL614741 | 0.86 | CASP3 (0.62) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL3140616 | 0.86 | CASP3 (0.62) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL29409608 | 0.85 | CASP3 (0.55) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18740358 | 0.85 | CASP3 (0.58) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20543505 | 0.85 | CASP3 (0.58) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL24213871 | 0.84 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL17494194 | 0.84 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879574-B2 | Folded peptide backbone each end of which is conjugated to a fluorophore, which when cleaved as by digestion with a protease, the fluorophores provide high intensity signals; histology | ONCOIMMUNIN, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20080199898-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-7312302-B2 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | ONCOLMMUNIN, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-20040096926-A1 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | ONCOIMMUNIN, INC. | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096926-A1 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | PRSS3, PREP, CTRL | CASP3 266/4885CASP7 233/4885CASP1 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.