Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RAC1 | P63000 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1597761 | 0.76 | BCL2L1 (0.53) | DRD1DRD2ACHE | |
| SCHEMBL30817469 | 0.76 | BCL2L1 (0.53) | DRD1DRD2ACHE | |
| SCHEMBL7271975 | 0.73 | EGFR (0.42) | DRD1DRD2ADRA2AADRA2BADRA2C | |
| SCHEMBL3797823 | 0.70 | BCL2L1 (0.56) | DRD1DRD2 | |
| SCHEMBL1535927 | 0.70 | BCL2L1 (0.50) | DRD1DRD2ACHE | |
| SCHEMBL19836046 | 0.68 | MAOA (0.32) | — | |
| SCHEMBL19835753 | 0.68 | HTR2A (0.48) | ADRA2AADRA2BADRA2C | |
| SCHEMBL16746123 | 0.67 | CNR1 (0.31) | — | |
| SCHEMBL6905745 | 0.66 | CA1 (0.36) | DRD1DRD2ADRA2AADRA2BADRA2C | |
| SCHEMBL23021747 | 0.66 | CYP2A13 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-A1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | Aventis Pharmaceuticals Inc. (US) | 2000-07-05 | — | — | EP | claimed |
| WO-1998034933-A1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-08-13 | — | — | WO | claimed |