⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606444 | 0.78 | — | — | |
| SCHEMBL6886486 | 0.77 | — | — | |
| SCHEMBL6605907 | 0.77 | DPP4 (0.32) | — | |
| SCHEMBL28857777 | 0.76 | — | — | |
| SCHEMBL3602233 | 0.76 | — | — | |
| SCHEMBL28659321 | 0.76 | — | — | |
| SCHEMBL19405402 | 0.75 | — | — | |
| SCHEMBL19405700 | 0.75 | — | — | |
| SCHEMBL1145033 | 0.75 | TRPA1 (0.32) | — | |
| SCHEMBL19405658 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996443-A1 | CERTAIN DIARYLIMIDAZOLE DERIVATIVES; A NEW CLASS OF NPY SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 2000-05-03 | — | — | EP | claimed |
| WO-1999001128-A1 | CERTAIN DIARYLIMIDAZOLE DERIVATIVES; A NEW CLASS OF NPY SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-01-14 | — | — | WO | claimed |