SCHEMBL8119857

SCHEMBL8119857

CN[C@@H](CCCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC(=O)NCCOCCOCCOCCOCCC(=O)NCCCC[C@H](NC)C(N)=O)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.44
▸ ALB P02768 3/20 0.42
▸ TSHR P16473 1/20 0.41
▸ FOLH1 Q04609 2/20 0.39
▸ EPOR P19235 1/20 0.37
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ SIRT5 Q9NXA8 1/20 0.34
▸ NOD1 Q9Y239 1/20 0.34
▸ CA12 O43570 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA4 P22748 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8115663 0.93 GLP1R (0.51) GLP1RALBTSHRFOLH1EPOR
SCHEMBL12972437 0.92 GLP1R (0.47) GLP1RALBTSHRFOLH1EPOR
SCHEMBL12972443 0.89 GLP1R (0.45) GLP1RALBTSHRFOLH1EPOR
SCHEMBL12972442 0.87 GLP1R (0.47) GLP1RALBTSHRFOLH1EPOR
SCHEMBL14500495 0.86 ALB (0.43) GLP1RALBTSHRFOLH1EPOR
SCHEMBL8116035 0.85 GLP1R (0.50) GLP1RALBTSHREPORMEN1
SCHEMBL14550361 0.85 GLP1R (0.56) GLP1RFOLH1EPORSIRT5
SCHEMBL13577551 0.85 GLP1R (0.56) GLP1RFOLH1EPORSIRT5
SCHEMBL14550509 0.85 GLP1R (0.56) GLP1RFOLH1EPORSIRT5
SCHEMBL14550390 0.85 GLP1R (0.56) GLP1RFOLH1EPORSIRT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders ARBOGAST CHRISTOPHE (FR) 2004-10-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders MKI67, TP53, VHL GLP1R 4619/4885ALB 1656/4885TSHR 4153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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