Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122770 | 0.85 | TDP1 (0.40) | TDP1MEN1KMT2A | |
| SCHEMBL8119790 | 0.83 | EPHX1 (0.44) | TDP1MEN1KMT2A | |
| SCHEMBL9195704 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4ATDP1SNCAMEN1 | |
| Hydrochloric Acid SCHEMBL8126066 | 0.78 | TDP1 (0.35) | TDP1MEN1KMT2A | |
| SCHEMBL1388852 | 0.77 | TPSAB1 (0.39) | TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8112935 | 0.76 | TPSAB1 (0.38) | TDP1MEN1KMT2A | |
| SCHEMBL9203185 | 0.76 | TDP1 (0.34) | TDP1MAPTHTTNPSR1MEN1 | |
| SCHEMBL8529359 | 0.76 | NPY1R (0.37) | MAPTHTTNPSR1MEN1KMT2A | |
| SCHEMBL8121716 | 0.76 | SLC6A4 (0.43) | TDP1MEN1KMT2A | |
| SCHEMBL8126608 | 0.76 | TDP1 (0.41) | TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |