SCHEMBL812018

SCHEMBL812018

O=C(c1ccc(Oc2ccccc2)cc1)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.66
POLB P06746 1/20 0.55
PARP10 Q53GL7 1/20 0.53
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53
BCL2L1 Q07817 1/20 0.51
MCL1 Q07820 1/20 0.51
SERPINE1 P05121 1/20 0.49
ITGA1 P56199 1/20 0.48
PGR P06401 1/20 0.48
ELANE P08246 1/20 0.47
AKR1C3 P42330 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032445 0.87 SRD5A2 (0.72) SRD5A2POLBPARP10HPGD
SCHEMBL19317526 0.87 SRD5A2 (0.78) SRD5A2POLBPARP10MCL1ELANE
SCHEMBL6521756 0.87 SRD5A2 (0.62) SRD5A2POLBPARP10SERPINE1PGR
SCHEMBL13599782 0.85 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL1082112 0.85 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL9536469 0.85 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL2866068 0.85 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL235530 0.85 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL6425494 0.84 SRD5A2 (0.67) SRD5A2POLBELANEHPGD
SCHEMBL23559522 0.83 SRD5A2 (0.62) SRD5A2POLBPARP10AKR1C3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390241-B1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP disclosed
US-8598349-B2 Method for manufacturing conjugated aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-03 US disclosed
EP-2390241-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-11-30 EP disclosed
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2011-11-10 US disclosed
US-20110256790-A1 THERMAL INSULATION CONTAINING SUPPLEMENTAL INFRARED RADIATION ABSORBING MATERIAL SAINT-GOBAIN ISOVER (FR) 2011-10-20 US disclosed
EP-0773249-B1 Polyphenylene co-polymers MISSISSIPPI POLYMER TECHNOLOGI (US) 2002-10-02 EP disclosed
US-5886130-A THE CO-POLYMERS ARE USEFUL AS MOLDING RESINS, AND COMPOSITE MATRIX RESINS, AND WHERE AR IS HETEROARYLENE AS ION EXCHANGE RESINS. MAXDEM INCORPORATED (US) 1999-03-23 US disclosed
EP-0773249-A1 Polyphenylene co-polymers MAXDEM INCORPORATED (US) 1997-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND C9, H1-10, CYP1A1 SRD5A2 3817/4885POLB 3065/4885PARP10 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.