SCHEMBL8120232

SCHEMBL8120232

Fc1ccc(Oc2nc(Oc3csc(C(F)(F)F)c3)c(F)c(F)c2F)cc1F

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
F10 P00742 2/20 0.32
MPL P40238 1/20 0.32
SOS1 Q07889 1/20 0.32
MAP4K4 O95819 1/20 0.32
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31
POLB P06746 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8111160 0.91 F10 (0.42) F10
SCHEMBL8119943 0.85 ALOX5 (0.36) CNR1CNR2
SCHEMBL8120351 0.81 F10 (0.41) F10SOS1
SCHEMBL8126929 0.80 F2 (0.37) F10MPL
SCHEMBL8120135 0.74 F10 (0.47) F10
SCHEMBL6175671 0.73 F2 (0.32) F10MPL
SCHEMBL8111772 0.73 F10 (0.49) F10
SCHEMBL8111396 0.69 F10 (0.36) F10POLB
SCHEMBL8119386 0.69 F10 (0.39) F10L3MBTL1
SCHEMBL8125826 0.69 SOS1 (0.34) SOS1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028959-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 2000-08-23 EP claimed
WO-1999024427-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 1999-05-20 WO claimed
US-5851952-A Herbicidal thienyloxyazines AMERICAN CYANAMID COMPANY (US) 1998-12-22 US claimed
EP-1028959-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 2000-08-23 EP disclosed
WO-1999024427-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 1999-05-20 WO disclosed
US-5851952-A Herbicidal thienyloxyazines AMERICAN CYANAMID COMPANY (US) 1998-12-22 US disclosed