SCHEMBL6175671

SCHEMBL6175671

Fc1cc(F)c(Oc2csc(C(F)(F)F)c2)nc1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.32
F10 P00742 1/20 0.32
MPL P40238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8126929 0.92 F2 (0.37) F2F10MPL
SCHEMBL6178955 0.75 PRMT6 (0.34)
SCHEMBL8111160 0.71 F10 (0.42) F2F10
SCHEMBL8121568 0.69 LMNA (0.34)
SCHEMBL5548596 0.69 CHRM5 (0.38) F10
SCHEMBL5214301 0.68 MAPT (0.36) F10
SCHEMBL8120351 0.68 F10 (0.41) F2F10
SCHEMBL8119943 0.68 ALOX5 (0.36)
SCHEMBL8119386 0.67 F10 (0.39) F2F10
SCHEMBL8125502 0.66 F10 (0.40) F2F10MPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1427725-B1 PYRAZOLYL-SUBSTITUTED THIENYLOXYPYRIDINES BASF AG (DE) 2005-03-23 EP disclosed
US-20040235667-A1 Pyrazolyl-substituted thienyloxypyridines BASF AKTIENGESELLSCHAFT (DE) 2004-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235667-A1 Pyrazolyl-substituted thienyloxypyridines HDHD5, CBR3, KCNH3 F2 3313/4885F10 4440/4885MPL 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.