Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676368 | 0.79 | MEN1 (0.38) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL4630703 | 0.79 | SLC6A3 (0.45) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL3466586 | 0.76 | L3MBTL1 (0.38) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL13316632 | 0.74 | KDM4C (0.36) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL5874214 | 0.74 | KDM4C (0.45) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL4258149 | 0.74 | L3MBTL1 (0.44) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL8350985 | 0.73 | KDM4C (0.49) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL4631262 | 0.72 | SLC6A3 (0.43) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL5199433 | 0.72 | KDM4C (0.38) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7674634 | 0.72 | L3MBTL1 (0.40) | KDM4CMEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559538-B1 | Quaternary salts of 4-substituted piperidines, their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2000-05-17 | — | — | EP | disclosed |
| US-5773620-A | Quaternary ammonium salts of aromatic amine compounds, their preparation and pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1998-06-30 | — | — | US | disclosed |
| US-5674881-A | NEUROKININ RECEPTOR ANTAGONISTS | ELF SANOFI (FR) | 1997-10-07 | — | — | US | disclosed |
| WO-1993018002-A1 | QUATERNARY SALTS OF 4-SUBSTITUTED PIPERIDINES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-09-16 | — | — | WO | disclosed |
| EP-0559538-A1 | Quaternary salts of 4-substituted piperidines, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1993-09-08 | — | — | EP | disclosed |