Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | EPOR | P19235 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121296 | 0.91 | F2 (0.38) | PRSS1ITGB3ITGA2BF2F10 | |
| SCHEMBL8122704 | 0.91 | TPSAB1 (0.36) | PRSS1ITGB3ITGA2BTMPRSS15TPSAB1 | |
| SCHEMBL8112784 | 0.90 | CNR1 (0.41) | ALDH1A1EPOR | |
| SCHEMBL8126542 | 0.90 | TDP1 (0.36) | PRSS1ITGB3ITGA2BTMPRSS15F2 | |
| SCHEMBL8128254 | 0.90 | TPSAB1 (0.38) | PRSS1ITGB3ITGA2BTMPRSS15F10 | |
| SCHEMBL8112714 | 0.89 | MEN1 (0.42) | PRSS1ITGB3ITGA2BF2F10 | |
| SCHEMBL8127029 | 0.88 | NPY1R (0.41) | EPOR | |
| SCHEMBL8120085 | 0.88 | CNR1 (0.36) | TPSAB1EPORTDP1 | |
| SCHEMBL8122513 | 0.88 | HDAC3 (0.37) | EPORTDP1 | |
| SCHEMBL8121122 | 0.88 | TMEM97 (0.42) | ITGB3ITGA2BTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |