Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13340712 | 1.00 | GPR119 (0.45) | GPR119AGTR2BCHENR1H2NR1H3 | |
| SCHEMBL14160138 | 0.88 | AGTR2 (0.46) | GPR119AGTR2BCHENR1H2NR1H3 | |
| SCHEMBL14085916 | 0.87 | NR1H3 (0.51) | GPR119AGTR2NR1H2NR1H3 | |
| SCHEMBL13340709 | 0.86 | AGTR2 (0.44) | GPR119AGTR2BCHENR1H2NR1H3 | |
| SCHEMBL12845090 | 0.86 | AGTR2 (0.46) | GPR119AGTR2BCHENR1H2NR1H3 | |
| SCHEMBL6337507 | 0.85 | AGTR2 (0.50) | GPR119AGTR2BCHENR1H2NR1H3 | |
| SCHEMBL6337504 | 0.85 | AGTR2 (0.50) | GPR119AGTR2BCHENR1H2NR1H3 | |
| SCHEMBL3492556 | 0.84 | AGTR2 (0.50) | AGTR2BCHE | |
| SCHEMBL13340714 | 0.83 | NR1H2 (0.44) | GPR119AGTR2NR1H2NR1H3TP53 | |
| SCHEMBL2017921 | 0.82 | NR1H2 (0.46) | GPR119AGTR2NR1H2NR1H3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |