SCHEMBL812116

SCHEMBL812116

C=CCCCCCCCC[SiH](Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ABCC4 O15439 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TRPA1 O75762 3/20 0.37
LPAR3 Q9UBY5 2/20 0.34
LMNA P02545 2/20 0.34
LPAR2 Q9HBW0 1/20 0.34
TDP1 Q9NUW8 2/20 0.31
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6037323 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL9715886 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL6037440 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL6037336 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL6037296 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL2684813 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL28353840 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL3891499 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL3629604 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL29001282 0.97 TSHR (0.44) TSHRABCC4MAPTALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184846-A High-melt-strength propylene polymer and preparation method thereof 湖南立为新材料有限公司 2024-06-14 CN claimed
CN-118063658-A Polybutene-1 and process for preparing same 中国科学院化学研究所 2024-05-24 CN claimed
CN-117903371-A Multiphase copolymer of polypropylene with branching or crosslinking, preparation method and application thereof 北京市科学技术研究院 2024-04-19 CN claimed
CN-111944234-B Method for preparing polyolefin in-kettle alloy and polyolefin in-kettle alloy prepared by method 中国科学院化学研究所 2022-01-11 CN claimed
CN-112143114-B Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2021-10-22 CN claimed
CN-112143113-B Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2021-09-21 CN claimed
CN-112142897-B Application of organosilane in preparation of linear low density polyethylene, linear low density polyethylene and preparation method and application thereof 中国科学院化学研究所 2021-07-27 CN claimed
CN-112142894-B Application of organosilane in preparation of high-density polyethylene, high-density polyethylene and preparation method and application thereof 中国科学院化学研究所 2021-05-25 CN claimed
CN-112143113-A Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112142897-A Application of organosilane in preparation of linear low density polyethylene, linear low density polyethylene and preparation method and application thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112143114-A Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112142894-A Application of organosilane in preparation of high-density polyethylene, high-density polyethylene and preparation method and application thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112142895-A Application of organosilane, random copolymerization polypropylene and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-111944234-A Method for preparing polyolefin in-kettle alloy and polyolefin in-kettle alloy prepared by method 中国科学院化学研究所 2020-11-17 CN claimed
CN-111138469-A Organosilane compound, polyolefin resin, and preparation method and application thereof 中国科学院化学研究所 2020-05-12 CN claimed
EP-2276793-B1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INT (FR) 2012-08-01 EP claimed
US-8063237-B2 Sulfur modified silanes for the elaboration of high refractive index materials ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2011-11-22 US claimed
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2011-03-31 US claimed
EP-2276793-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS Essilor International (Compagnie Générale d'Optique) (FR) 2011-01-26 EP claimed
WO-2009138853-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS TST, LAGE3, PSME1 TSHR 3396/4885ABCC4 4075/4885MAPT 1086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.