Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848422 | 0.81 | PGK1 (0.44) | PGK1PGK2BCHE | |
| SCHEMBL20535750 | 0.81 | PGK1 (0.36) | PGK1PGK2BCHEMAPTENPP2 | |
| SCHEMBL20536453 | 0.80 | PGK1 (0.46) | PGK1PGK2ENPP2HDAC1HDAC6 | |
| SCHEMBL20536552 | 0.77 | PGK1 (0.43) | PGK1PGK2HDAC1HDAC6 | |
| SCHEMBL3556536 | 0.74 | PGK1 (0.47) | PGK1PGK2MAPTGAA | |
| SCHEMBL8123118 | 0.74 | ALDH1A1 (0.45) | MAPTGAA | |
| SCHEMBL8911401 | 0.73 | SCN9A (0.33) | BCHEMAPTTP53HDAC1HDAC6 | |
| SCHEMBL20535736 | 0.73 | PGK1 (0.34) | PGK1PGK2ENPP2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL7178258 | 0.73 | ALDH1A1 (0.47) | MAPTGAA | |
| SCHEMBL8911398 | 0.72 | NPC1 (0.33) | BCHEMAPTTP53HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691962-B1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AG (DE) | 2000-09-13 | — | — | EP | disclosed |
| EP-0691962-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022842-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |