Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.36 |
| ▸ | CHRNG | P07510 | 3/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.36 |
| ▸ | CHRND | Q07001 | 3/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129753 | 0.88 | BCHE (0.40) | — | |
| SCHEMBL8119334 | 0.88 | NPY1R (0.47) | NPY1RNPFFR1NPFFR2NPY5RNPY2R | |
| SCHEMBL8120923 | 0.87 | NPY1R (0.39) | NPY1RTLR2MC4RMC3RMC1R | |
| SCHEMBL8119335 | 0.85 | TRPV1 (0.41) | NPY1R | |
| SCHEMBL8127804 | 0.85 | GAA (0.41) | NPY1RMC4RMC3RMC1R | |
| SCHEMBL8120771 | 0.84 | NPY1R (0.44) | NPY1RNPFFR1NPFFR2NPY5ROPRK1 | |
| SCHEMBL4650707 | 0.83 | NPY1R (0.43) | NPY1RCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL8122078 | 0.83 | CASR (0.44) | NPY1RTLR2CNR1 | |
| SCHEMBL8128352 | 0.83 | PADI4 (0.39) | NPY1RMC4RMC3RMC1RF2 | |
| SCHEMBL8120228 | 0.81 | NPY1R (0.38) | NPY1RTLR2NPY5RF10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |