Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.40 |
| ▸ | NPY4R | P50391 | 7/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120019 | 0.89 | ITGB3 (0.41) | CNR1CNR2 | |
| SCHEMBL8119334 | 0.89 | NPY1R (0.47) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8126974 | 0.84 | ASAH1 (0.41) | CNR1CNR2 | |
| SCHEMBL8122083 | 0.84 | NPY1R (0.40) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8127573 | 0.84 | MTNR1A (0.42) | — | |
| SCHEMBL4652031 | 0.83 | NPY1R (0.48) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8529501 | 0.82 | NPY1R (0.38) | NPY1RNPY5RNPY4RCNR1CNR2 | |
| SCHEMBL8120923 | 0.81 | NPY1R (0.39) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8122078 | 0.81 | CASR (0.44) | NPY1RCNR1CNR2 | |
| SCHEMBL8112874 | 0.81 | KMT2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |