Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 5/20 | 0.38 |
| ▸ | MC1R | Q01726 | 5/20 | 0.38 |
| ▸ | MC3R | P41968 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | MC5R | P33032 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751693 | 0.85 | MC4R (0.44) | PADI4PADI2MC4RMC1RMC3R | |
| SCHEMBL8122083 | 0.83 | NPY1R (0.40) | MC4RMC1RMC3RF2NPY1R | |
| SCHEMBL8120923 | 0.83 | NPY1R (0.39) | MC4RMC1RMC3RNPY1R | |
| SCHEMBL8127804 | 0.82 | GAA (0.41) | MC4RMC1RMC3RNPY1R | |
| SCHEMBL9268042 | 0.82 | SLC6A2 (0.36) | PADI4PADI2MC4RMC1RMC3R | |
| SCHEMBL8119334 | 0.81 | NPY1R (0.47) | NPY1R | |
| SCHEMBL8122078 | 0.81 | CASR (0.44) | NPY1RITGB3ITGA2B | |
| SCHEMBL8119335 | 0.81 | TRPV1 (0.41) | NPY1R | |
| SCHEMBL8129753 | 0.80 | BCHE (0.40) | — | |
| SCHEMBL8120228 | 0.79 | NPY1R (0.38) | F2NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |