Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121919 | 0.86 | NPY1R (0.35) | F2ADAM17 | |
| SCHEMBL8126685 | 0.82 | F2 (0.40) | F2MGLLADAM17KMT2A | |
| SCHEMBL8120727 | 0.81 | F2 (0.39) | F2 | |
| SCHEMBL9271189 | 0.80 | NPY1R (0.37) | F2ADAM17 | |
| SCHEMBL8121207 | 0.77 | NPY1R (0.35) | F2ADAM17 | |
| SCHEMBL9196848 | 0.76 | EPOR (0.32) | — | |
| SCHEMBL8112864 | 0.74 | F2 (0.36) | F2ADAM17KMT2A | |
| SCHEMBL8126120 | 0.73 | CA12 (0.36) | F2ADAM17KMT2A | |
| SCHEMBL8112880 | 0.73 | CA1 (0.34) | F2 | |
| SCHEMBL8120451 | 0.73 | F2 (0.36) | F2ADAM17KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |