Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 7/20 | 0.32 |
| ▸ | NPY2R | P49146 | 5/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271189 | 0.93 | NPY1R (0.37) | NPY1RF2ADAM17TMEM97SIGMAR1 | |
| SCHEMBL8121207 | 0.90 | NPY1R (0.35) | NPY1RF2ADAM17NPY4RNPY2R | |
| SCHEMBL8122834 | 0.86 | F2 (0.37) | F2ADAM17 | |
| SCHEMBL8120806 | 0.84 | ADAM17 (0.36) | NPY1RF2ADAM17NPY4RNPY2R | |
| SCHEMBL8112864 | 0.83 | F2 (0.36) | NPY1RF2ADAM17 | |
| SCHEMBL8121913 | 0.82 | NPY4R (0.35) | NPY1RF2ADAM17NPY4RNPY2R | |
| SCHEMBL8123419 | 0.82 | TRPV1 (0.37) | NPY1RF2NPY2RNPY5R | |
| SCHEMBL8124247 | 0.81 | NPY1R (0.42) | NPY1RF2NPY4RNPY5R | |
| Hydrochloric Acid SCHEMBL8119516 | 0.81 | NPY1R (0.39) | NPY1RF2NPY4RNPY5R | |
| SCHEMBL8125832 | 0.80 | F2 (0.36) | NPY1RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |