Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121919 | 0.93 | NPY1R (0.35) | NPY1RF2TMEM97SIGMAR1MTOR | |
| SCHEMBL8121207 | 0.85 | NPY1R (0.35) | NPY1RF2TMEM97SIGMAR1ADAM17 | |
| SCHEMBL8121913 | 0.82 | NPY4R (0.35) | NPY1RF2MTORADAM17 | |
| SCHEMBL8122834 | 0.80 | F2 (0.37) | F2ADAM17 | |
| SCHEMBL8120806 | 0.79 | ADAM17 (0.36) | NPY1RF2ADAM17 | |
| SCHEMBL8123419 | 0.79 | TRPV1 (0.37) | NPY1RF2PLGPRSS1 | |
| Hydrochloric Acid SCHEMBL8119516 | 0.78 | NPY1R (0.39) | NPY1RF2 | |
| SCHEMBL8124247 | 0.78 | NPY1R (0.42) | NPY1RF2 | |
| SCHEMBL8112864 | 0.78 | F2 (0.36) | NPY1RF2ADAM17 | |
| SCHEMBL8125832 | 0.78 | F2 (0.36) | NPY1RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |