Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | NPY1R | P25929 | 4/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119401 | 0.86 | CNR1 (0.48) | CNR1CNR2NPY1RC3AR1 | |
| SCHEMBL8120358 | 0.86 | CNR1 (0.51) | CNR1CNR2C3AR1 | |
| SCHEMBL8068044 | 0.84 | CNR1 (0.41) | CNR1CNR2NPY1RC3AR1NPY5R | |
| SCHEMBL1388522 | 0.84 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL8587072 | 0.83 | NPY1R (0.52) | NPY1RNPY5R | |
| SCHEMBL3817640 | 0.83 | NPY1R (0.51) | CNR1CNR2NPY1RNPY5R | |
| SCHEMBL9201253 | 0.82 | CTSD (0.45) | CNR1CNR2NPY1RNPY5RMEN1 | |
| SCHEMBL9201265 | 0.82 | CTSD (0.45) | CNR1CNR2NPY1RNPY5RMEN1 | |
| SCHEMBL5057899 | 0.82 | NPY1R (0.53) | NPY1RNPY5R | |
| SCHEMBL1388524 | 0.81 | NPY1R (0.49) | CNR1CNR2NPY1RC3AR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | claimed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | claimed |